Free radical biology - terminology and critical thinking

被引：155

作者：

Azzi, A

Davies, KJA

Kelly, F

机构：

[1] Univ Bern, Inst Biochem & Mol Biol, CH-3012 Bern, Switzerland

[2] Univ So Calif, Ethel Percy Andrus Gerontol Ctr, Los Angeles, CA 90089 USA

[3] Kings Coll London, Sch Life & Hlth Sci, Environm Res Grp, London WC2R 2LS, England

来源：

FEBS LETTERS | 2004年 / 558卷 / 1-3期

关键词：

antioxidant; free radical; vitamin E; tocophenol; signal transduction;

D O I：

10.1016/S0014-5793(03)01526-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

What is an antioxidant? Can one, at a cellular level, speak of direct and indirect antioxidants? Can oxidative stress be quantified and characterized? What are the oxidant species that may have regulatory functions in a cell? Since the above concepts have become of frequent use in all Journals it may be appropriate if some critical thinking outlined in this review could become available to a broad public. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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页码：3 / 6

页数：4

相关论文

共 65 条

[1]

Antioxidant role of melatonin in lipid peroxidation of human LDL [J].

Abuja, PM ;

Liebmann, P ;

Hayn, M ;

Schauenstein, K ;

Esterbauer, H .

FEBS LETTERS, 1997, 413 (02) :289-293

[2]

Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust [J].

Aoki, Y ;

Sato, H ;

Nishimura, N ;

Takahashi, S ;

Itoh, K ;

Yamamoto, M .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 2001, 173 (03) :154-160

[3]

Azzi A, 2002, FREE RADICAL RES, V36, P30

[4]

Hydrogen peroxide activates p70S6k signaling pathway [J].

Bae, GU ;

Seo, DW ;

Kwon, HK ;

Lee, HY ;

Hong, S ;

Lee, ZW ;

Ha, KS ;

Lee, HW ;

Han, JW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (46) :32596-32602

[5]

Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention [J].

Bagchi, D ;

Bagchi, M ;

Stohs, SJ ;

Das, DK ;

Ray, SD ;

Kuszynski, CA ;

Joshi, SS ;

Pruess, HG .

TOXICOLOGY, 2000, 148 (2-3) :187-197

[6]

Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cells [J].

Baulig, A ;

Garlatti, M ;

Bonvallot, V ;

Marchand, A ;

Barouki, R ;

Marano, F ;

Baeza-Squiban, A .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2003, 285 (03) :L671-L679

[7]

Protective role of phospholipid oxidation products in endotoxin-induced tissue damage [J].

Bochkov, VN ;

Kadl, A ;

Huber, J ;

Gruber, F ;

Binder, BR ;

Leitinger, N .

NATURE, 2002, 419 (6902) :77-81

[8]

The European perspective on vitamin E:: current knowledge and future research [J].

Brigelius-Flohé, R ;

Kelly, FJ ;

Salonen, JT ;

Neuzil, J ;

Zingg, JM ;

Azzi, A .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2002, 76 (04) :703-716

[9]

Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay [J].

Bruggisser, R ;

von Daeniken, K ;

Jundt, G ;

Schaffner, W ;

Tullberg-Reinert, H .

PLANTA MEDICA, 2002, 68 (05) :445-448

[10]

ASCORBATE FREE-RADICAL AS A MARKER OF OXIDATIVE STRESS - AN EPR STUDY [J].

BUETTNER, GR ;

JURKIEWICZ, BA .

FREE RADICAL BIOLOGY AND MEDICINE, 1993, 14 (01) :49-55

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