SPLATCHE: a program to simulate genetic diversity taking into account environmental heterogeneity

被引：115

作者：

Currat, M

Ray, N

Excoffier, L

机构：

[1] Univ Bern, Inst Zool, Computat & Mol Populat Genet Lab, CH-3012 Bern, Switzerland

[2] Univ Geneva, Anthropol & Ecol Dept, Genet & Biomet Lab, CH-1227 Carouge, Switzerland

来源：

MOLECULAR ECOLOGY NOTES | 2004年 / 4卷 / 01期

关键词：

coalescent simulation; demography; heterogeneous environment; molecular diversity; spatial expansion;

D O I：

10.1046/j.1471-8286.2003.00582.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We present a program called SPLATCHE (SPatial, And Temporal Coalescences in Heterogeneous Environments) to simulate the molecular diversity of samples of genes in an environmentally heterogeneous world. Simulations are performed by, first, simulating the colonization of the world using environmental information to constrain migrations and local densities. These simulated densities and migration rates recorded over time and space are then used to simulate genetic diversity under a coalescent framework. The program thus virtually allows the translation of ecological information into molecular diversity.

引用

页码：139 / 142

页数：4

共 12 条

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