EPIMAG: International Cross-Sectional Epidemiological Psoriasis Study in the Maghreb

被引：17

作者：

Ammar-Khodja, Aomar ^{[1
]}

Benkaidali, Ismail ^{[1
]}

Bouadjar, Bakar ^{[2
]}

Serradj, Amina ^{[3
]}

Titi, Abdelhamid ^{[4
]}

Benchikhi, Hakima ^{[5
]}

Amal, Said ^{[6
]}

Hassam, Badreddine ^{[7
]}

Sekkat, Abdelhak ^{[8
]}

Mernissi, Fatima Zahra ^{[9
]}

Mokhtar, Incaf ^{[10
]}

Dahoui, Raouf ^{[11
]}

Denguezli, Mohamed ^{[12
]}

Doss, Nejib ^{[11
]}

Turki, Hamida ^{[13
]}

机构：

[1] CHU Mustapha, Dept Dermatol, Algiers, Algeria

[2] Univ Algiers, CHU Bab El Oued, Dept Dermatol, Algiers, Algeria

[3] Univ Oran, EHS Oran, Dept Dermatol, Oran, Algeria

[4] Univ Annaba, CHU Annaba, Dept Dermatol, Annaba, Algeria

[5] CHU Ibn Rochd, Dept Dermatol, Casablanca, Morocco

[6] CHU Mohammed V, Dept Dermatol, Marrakech, Morocco

[7] CHU Ibn Sina, Dept Dermatol, Rabat, Morocco

[8] Cheikh Zaid Hosp, Dept Dermatol, Rabat, Morocco

[9] CHU Hassan II, Dept Dermatol, Fes, Morocco

[10] Habib Thameur Hosp, Dept Dermatol, Tunis, Tunisia

[11] Mil Hosp Instruct Tunis, Dept Dermatol, Tunis, Tunisia

[12] CHU Farhat Hached, Dept Dermatol, Sousse, Tunisia

[13] CHU Hedi Chaker, Dept Dermatol, Sfax, Tunisia

来源：

DERMATOLOGY | 2015年 / 231卷 / 02期

关键词：

Psoriasis; Epidemiology; Characterization; Screening; Prevalence; Frequency; DIABETES-MELLITUS; POPULATION; RISK; PREVALENCE; ASSOCIATION; DISEASES; OBESITY; BURDEN; ADULTS; COMMON;

D O I：

10.1159/000382123

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100227 [皮肤病学];

摘要：

Background: Psoriasis is a common skin disorder that is characterized by red plaques covered with silvery scales and is associated with considerable psychosocial impact. It has been described in several studies worldwide, but specific data from the Maghreb (Algeria, Morocco and Tunisia) are unavailable. Objectives: To characterize the frequency of new psoriasis cases and to describe the epidemiological and clinical profile of psoriasis in the Maghreb. Methods: A psoriasis working group for the Maghreb initiated the EPIMAG international multicentre cross-sectional observational epidemiological study coupled with a 2-week psoriasis screening study via medical consultation. Data were collected via questionnaires. Results: The total analysis population included 373 pre-existing and 326 new psoriasis cases, described by 261 participating investigators. The frequency of new psoriasis cases was 10.26/1,000 in Algeria, 15.04/1,000 in Morocco and 13.26/1,000 in Tunisia, and thus 12.08/1,000 in the Maghreb. In all 699 psoriasis subjects, the mean age was 46 years, the mean BMI was 26.6, and 55.7% of subjects were men. Two thirds of the subjects had never smoked, and 85.0% had never consumed alcohol. Half had brown skin, and 28.6% had a family history of psoriasis. Three quarters had localized psoriasis, 85.8% had plaque psoriasis, coupled with pruritus in over 70.0% of cases. Flares or outbreaks were most often triggered by stress (79.4%) and change of season (43.1%). The majority of subjects used topical therapy, and the investigators considered overall treatment efficacy to be partial in over half of the cases. Among patients with preexisting psoriasis, secondary analyses showed that 73.2% had severe psoriasis, and that quality of life was severely affected in 40.1% of cases. The mean number of missing school or work days over 6 months was 3.2 (+/- 12.1) days. Conclusions: Our study provides novel information relative to psoriasis epidemiology and characterization in the Maghreb and highlights the need to improve psoriasis screening and management in the region. The data will help optimize psoriasis management, to ensure appropriate national health care policies. (C) 2015 S. Karger AG, Basel

引用

页码：134 / 144

页数：11

共 42 条

[1]

Impact of psoriasis on quality of life in Kuwait [J].