Improvement of the enantioselectivity in the enantioselective hydrogenation of ethyl pyruvate by addition of achiral tertiary amines

被引：31

作者：

Margitfalvi, JL ^{[1
]}

Tálas, E ^{[1
]}

Hegedûs, M ^{[1
]}

机构：

[1] Hungarian Acad Sci, Chem Res Ctr, Inst Chem, H-1025 Budapest, Hungary

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 07期

关键词：

D O I：

10.1039/a900681h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the asymmetric hydrogenation of ethyl pyruvate over the catalyst system cinchonidine-Pt/Al2O3 the enantioselectivity was significantly improved by addition of different achiral tertiary amines to the reaction mixture, however the effect appeared to be strongly solvent and concentration dependent.

引用

页码：645 / 646

页数：2

共 13 条

[1] Enantioselective heterogeneous catalysis .2. Examination of the formation of the individual (R) and (S) lactates in the cinchonidine modified platinum hydrogenation of pyruvate [J].

Augustine, RL ;

Tanielyan, SK .

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 1996, 112 (01) :93-104

[2]

Blaser H. U., 1988, STUD SURF SCI CATAL, P153

[3] ENANTIOSELECTIVE HYDROGENATION OF ETHYL PYRUVATE - KINETIC MODELING OF THE MODIFICATION OF PT CATALYSTS BY CINCHONA ALKALOIDS [J].

BLASER, HU ;

GARLAND, M ;

JALLET, HP .

JOURNAL OF CATALYSIS, 1993, 144 (02) :569-578

[4] Enantioselective hydrogenation of alpha-ketoesters using cinchona modified platinum catalysts and related systems: A review [J].

Blaser, HU ;

Jalett, HP ;

Muller, M ;

Studer, M .

CATALYSIS TODAY, 1997, 37 (04) :441-463

[5] ORIGIN OF ENHANCED RATE IN THE PLATINUM-CATALYSED ENANTIOSELECTIVE HYDROGENATION OF METHYL PYRUVATE [J].

Bond, G. ;

Meheux, P. A. ;

Ibbotson, A. ;

Wells, P. B. .

CATALYSIS TODAY, 1991, 10 (03) :371-378

[6]

Margitfalvi JL, 1998, CHEM INDUST, V75, P531

[7]

Margitfalvi JL, 1996, STUD SURF SCI CATAL, V101, P241

[8] Enantioselective hydrogenation of alpha-keto esters over cinchona-Pt/Al2O3 catalysts - New interpretation of the rate acceleration and the induction of enantio-differentiation [J].

Margitfalvi, JL ;

Hegedus, M .

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 1996, 107 (1-3) :281-289

[9] CINCHONA-MODIFIED PT AS A CATALYST FOR ENANTIOSELECTIVE HYDROGENATION - CRITICISM OF THE TEMPLATE MODEL [J].

MARGITFALVI, JL ;

HEGEDUS, M .

JOURNAL OF CATALYSIS, 1995, 156 (01) :175-179

[10]

MARGITFALVI JL, 1993, NEW FRONTIERS CATALY, P2471

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