Electrochemical sensing DNA damage with nano-titanium dioxide and repair with a medicinal herb species resveratrol

被引：24

作者：

Chen, Guifang

Zhao, Jing

Liu, Xinjian

Gao, Ge

Huang, Junyi

Li, Genxi ^{[1
]}

机构：

[1] Nanjing Univ, Dept Biochem, Nanjing 210093, Peoples R China

[2] Nanjing Univ, Natl Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China

[3] Shanghai Univ, Sch Life Sci, Shanghai 200444, Peoples R China

[4] Shanghai Univ, Shanghai Key Lab Bioenergy Crops, Shanghai 200444, Peoples R China

来源：

JOURNAL OF BIOTECHNOLOGY | 2007年 / 127卷 / 04期

基金：

中国国家自然科学基金;

关键词：

electrochemical; DNA damage; nanoparticles; resveratrol;

D O I：

10.1016/j.jbiotec.2006.07.029

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

We have developed a simple electrochemical method to detect DNA damage caused by the photovoltaic effect of nano-TiO2. Meanwhile, we have found that resveratrol, a Chinese Traditional Medicinal Herb species, can have a repairing effect to the oxidized DNA, which can also be detected with the proposed technique in this paper. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：653 / 656

页数：4

共 16 条

[1]

MONO- + BIS-(2,2]-BIPYRIDINE) + )1,10-PHENANTHROLINE) CHELATES OF RUTHENIUM + OSMI17 .4. BIS CHELATES OF BIVALENT + TERVALENT OSMIUM [J].