Penicillin G acylase mediated synthesis of the enantiopure(S)-3-amino-azetidin-2-one

被引：21

作者：

Cainelli, G

Giacomini, D

Galletti, P

DaCol, M

机构：

[1] UNIV BOLOGNA, DIPARTIMENTO CHIM G CIAMICIAN, I-40126 BOLOGNA, ITALY

[2] BIOCHIM OPOS SPA, I-20041 AGRATE BRIANZA, ITALY

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 19期

关键词：

D O I：

10.1016/S0957-4166(97)00405-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A detailed study of the influence of temperature, pH and enzyme amount on the enantiomeric excess in the enzymatic resolution of N-1 protected 3-amino-azetidin-2-ones with supported PGA is presented. Both enantiomers could be obtained in good enantiomeric excess. (C) 1997 Elsevier Science Ltd.

引用

页码：3231 / 3235

页数：5

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