Optical trapping: A versatile technique for biomanipulation

被引:34
作者
Kuyper, CL [1 ]
Chiu, DT [1 ]
机构
[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA
关键词
D O I
10.1366/00037020260377652
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
With exciting advances in the spectroscopic imaging of biological molecules and the onset of single-molecule detection, optical trapping offers a complementary, versatile, and powerful technique for manipulating a wide array of biologically relevant particles in solution. Optical trapping offers useful means for measuring forces in the piconewton range, for observing displacements with nanometer resolution, and for the controlled initiation of dynamic processes with precise start times. The ease with which optical trapping can be integrated with microscopy techniques will make it an invaluable addition to a biologist's toolbox.
引用
收藏
页码:300A / 312A
页数:13
相关论文
共 99 条
[1]   Tying a molecular knot with optical tweezers [J].
Arai, Y ;
Yasuda, R ;
Akashi, K ;
Harada, Y ;
Miyata, H ;
Kinosita, K ;
Itoh, H .
NATURE, 1999, 399 (6735) :446-448
[2]   FORCES OF A SINGLE-BEAM GRADIENT LASER TRAP ON A DIELECTRIC SPHERE IN THE RAY OPTICS REGIME [J].
ASHKIN, A .
BIOPHYSICAL JOURNAL, 1992, 61 (02) :569-582
[3]   Optical trapping and manipulation of neutral particles using lasers [J].
Ashkin, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (10) :4853-4860
[4]   OBSERVATION OF A SINGLE-BEAM GRADIENT FORCE OPTICAL TRAP FOR DIELECTRIC PARTICLES [J].
ASHKIN, A ;
DZIEDZIC, JM ;
BJORKHOLM, JE ;
CHU, S .
OPTICS LETTERS, 1986, 11 (05) :288-290
[5]   FORCE GENERATION OF ORGANELLE TRANSPORT MEASURED INVIVO BY AN INFRARED-LASER TRAP [J].
ASHKIN, A ;
SCHUTZE, K ;
DZIEDZIC, JM ;
EUTENEUER, U ;
SCHLIWA, M .
NATURE, 1990, 348 (6299) :346-348
[6]   OPTICAL TRAPPING AND MANIPULATION OF SINGLE CELLS USING INFRARED-LASER BEAMS [J].
ASHKIN, A ;
DZIEDZIC, JM ;
YAMANE, T .
NATURE, 1987, 330 (6150) :769-771
[7]   OPTICAL LEVITATION BY RADIATION PRESSURE [J].
ASHKIN, A ;
DZIEDZIC, JM .
APPLIED PHYSICS LETTERS, 1971, 19 (08) :283-&
[8]   ACCELERATION AND TRAPPING OF PARTICLES BY RADIATION PRESSURE [J].
ASHKIN, A .
PHYSICAL REVIEW LETTERS, 1970, 24 (04) :156-&
[9]   IDENTIFICATION OF DEOXYRIBONUCLEASE-II AS AN ENDONUCLEASE INVOLVED IN APOPTOSIS [J].
BARRY, MA ;
EASTMAN, A .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1993, 300 (01) :440-450
[10]   Stretching of single collapsed DNA molecules [J].
Baumann, CG ;
Bloomfield, VA ;
Smith, SB ;
Bustamante, C ;
Wang, MD ;
Block, SM .
BIOPHYSICAL JOURNAL, 2000, 78 (04) :1965-1978