Emergent global oscillations in heterogeneous excitable media:: The example of pancreatic β cells

被引:55
作者
Cartwright, JHE [1 ]
机构
[1] Univ Granada, Lab Estudios Cristalog, IACT, CSIC, E-18071 Granada, Spain
来源
PHYSICAL REVIEW E | 2000年 / 62卷 / 01期
关键词
D O I
10.1103/PhysRevE.62.1149
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
Using the standard van der Pol-FitzHugh-Nagumo excitable medium model, I demonstrate a generic mechanism, diversity, that provokes the emergence of global oscillations from individually quiescent elements in heterogeneous excitable media. This mechanism may be operating in the mammalian pancreas, where excitable beta cells, quiescent when isolated, are found to oscillate when coupled, despite the absence of a pacemaker region.
引用
收藏
页码:1149 / 1154
页数:6
相关论文
共 48 条
[1]  
ANDREU E, UNPUB
[2]   ON THE STABILITY OF COUPLED CHEMICAL OSCILLATORS [J].
BARELI, K .
PHYSICA D, 1985, 14 (02) :242-252
[3]   DISORDER-ENHANCED SYNCHRONIZATION [J].
BRAIMAN, Y ;
DITTO, WL ;
WIESENFELD, K ;
SPANO, ML .
PHYSICS LETTERS A, 1995, 206 (1-2) :54-60
[4]   TAMING SPATIOTEMPORAL CHAOS WITH DISORDER [J].
BRAIMAN, Y ;
LINDNER, JF ;
DITTO, WL .
NATURE, 1995, 378 (6556) :465-467
[5]   Burridge-Knopoff models as elastic excitable media [J].
Cartwright, JHE ;
HernandezGarcia, E ;
Piro, O .
PHYSICAL REVIEW LETTERS, 1997, 79 (03) :527-530
[6]   Dynamics of elastic excitable media [J].
Cartwright, JHE ;
Eguíluz, VM ;
Hernández-García, E ;
Piro, O .
INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS, 1999, 9 (11) :2197-2202
[7]   APERIODIC STOCHASTIC RESONANCE IN EXCITABLE SYSTEMS [J].
COLLINS, JJ ;
CHOW, CC ;
IMHOFF, TT .
PHYSICAL REVIEW E, 1995, 52 (04) :R3321-R3324
[8]   ELECTRICAL ACTIVITY IN PANCREATIC ISLET CELLS [J].
DEAN, PM ;
MATTHEWS, EK .
NATURE, 1968, 219 (5152) :389-&
[9]   OSCILLATOR DEATH IN POPULATIONS OF ALL TO ALL COUPLED NONLINEAR OSCILLATORS [J].
ERMENTROUT, GB .
PHYSICA D, 1990, 41 (02) :219-231
[10]   PHASE LOCKING, PERIOD DOUBLING, AND CHAOTIC PHENOMENA IN EXTERNALLY DRIVEN EXCITABLE SYSTEMS [J].
FEINGOLD, M ;
GONZALEZ, DL ;
PIRO, O ;
VITURRO, H .
PHYSICAL REVIEW A, 1988, 37 (10) :4060-4063