Leflunomide as adjuvant treatment of dermatomyositis

被引:26
作者
Boswell, J. Scott [1 ]
Costner, Melissa I. [1 ]
机构
[1] Univ Texas SW Med Ctr Dallas, Dept Dermatol, Dallas, TX 75390 USA
关键词
D O I
10.1016/j.jaad.2007.08.014
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 [皮肤病与性病学];
摘要
We report 3 cases of recalcitrant dermatomyositis that responded to the addition of daily leflunomide, a novel immunomodulatory drug that is currently used to treat rheumatoid arthritis. In our patients, leflunomide proved both safe and effective as adjuvant therapy in treating dermatomyositis. © 2008 American Academy of Dermatology, Inc.
引用
收藏
页码:403 / 406
页数:4
相关论文
共 29 条
[1]
Peripheral neuropathy in patients on leflunomide [J].
Bharadwaj, A ;
Haroon, N .
RHEUMATOLOGY, 2004, 43 (07) :934-934
[2]
Peripheral neuropathy in patients treated with leflunomide [J].
Bonnel, RA ;
Graham, DJ .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2004, 75 (06) :580-585
[3]
Leflunomide: mode of action in the treatment of rheumatoid arthritis [J].
Breedveld, FC ;
Dayer, JM .
ANNALS OF THE RHEUMATIC DISEASES, 2000, 59 (11) :841-849
[4]
Peripheral neuropathy: an unwanted effect of leflunomide? [J].
Carulli, MT ;
Davies, UM .
RHEUMATOLOGY, 2002, 41 (08) :952-953
[5]
Leflunomide induced vasculitis - a dose-response relationship [J].
Chan, ATY ;
Bradlow, A ;
McNally, J .
RHEUMATOLOGY, 2003, 42 (03) :492-493
[6]
Leflunomide-associated pancytopenia with or without methotrexate [J].
Chan, J ;
Sanders, DC ;
Du, L ;
Pillans, PI .
ANNALS OF PHARMACOTHERAPY, 2004, 38 (7-8) :1206-1211
[7]
Polymyositis and dermatomyositis [J].
Dalakas, MC ;
Hohlfeld, R .
LANCET, 2003, 362 (9388) :971-982
[8]
Erythema multiforme-like drug eruption with oral involvement after intake of leflunomide [J].
Fischer, TW ;
Bauer, HI ;
Graefe, T ;
Barta, U ;
Elsner, P .
DERMATOLOGY, 2003, 207 (04) :386-389
[9]
Mycophenolate mofetil and leflunomide: promising compounds for the treatment of skin diseases [J].
Frieling, U ;
Luger, TA .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2002, 27 (07) :562-570
[10]
Lupus erythematosus with leflunomide: induction or reactivation? [J].
Gensburger, D ;
Kawashima, M ;
Marotte, H ;
Kanitakis, J ;
Miossec, P .
ANNALS OF THE RHEUMATIC DISEASES, 2005, 64 (01) :153-155