Alemtuzumab (Campath-1H) induction in a pediatric heart transplant: Successful outcome and rationale for its use

被引：16

作者：

Das, Bibhuti ^{[1
]}

Shoemaker, Lawrence ^{[2
]}

Recto, Michael ^{[1
]}

Austin, Erle ^{[3
]}

Dowling, Robert ^{[3
]}

机构：

[1] Univ Louisville, Dept Pediat, Div Cardiol, Louisville, KY 40202 USA

[2] Univ Louisville, Dept Pediat, Div Nephrol, Louisville, KY 40202 USA

[3] Univ Louisville, Dept Surg, Div Cardiothorac Surg, Louisville, KY 40202 USA

来源：

JOURNAL OF HEART AND LUNG TRANSPLANTATION | 2008年 / 27卷 / 02期

关键词：

D O I：

10.1016/j.healun.2007.11.569

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Despite increasing clinical experience in adult transplantation, induction therapy with alemtuzumab (Campath-1H) has rarely been reported in pediatric solid-organ transplants, and has been limited to kidneys, intestine and multi-visceral organs. Basic science research and clinical observations reported from the adult experience suggest potential benefits of alemtuzumab in pediatric organ recipients. We report successful induction therapy with alemtuzumab and steroid-free maintenance therapy for cardiac transplantation in a teenager, and discuss its merits in this patient.

引用

页码：242 / 244

页数：3

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