On the fetal magnetocardiogram

被引:13
作者
Peters, MJ
Stinstra, JG
van den Broek, SP
Huirne, JAF
Quartero, HWF
ter Brake, HJM
Rogalla, H
机构
[1] Univ Twente, Fac Appl Phys, Grad Sch Integrated Biomed Engn Restorat Human Fu, NL-7500 AE Enschede, Netherlands
[2] Hosp Med Spectrum Twente, Enschede, Netherlands
来源
BIOELECTROCHEMISTRY AND BIOENERGETICS | 1998年 / 47卷 / 02期
关键词
fetal magnetocardiogram; magnetic field; bioelectromagnetics; modelling;
D O I
10.1016/S0302-4598(98)00199-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Fetal magnetocardiography is a non-invasive technique for studying the electrical activity of the fetal heart. Fetal magnetocardiograms (fMCG) can be used to diagnose and classify fetal cardiac arrhythmias reliably: An averaged fMCG shows a QRS-complex, a P-wave, and a T-wave. However, it is still unknown if the currents in the tissues surrounding the fetal heart disturb these features. Furthermore, the measuring technique is not yet optimised for fMCG registrations. Simulation studies may provide guidelines for the design of an appropriate magnetometer system. Therefore, finite-element and boundary-element models were constructed in order to study the possible influence of the volume conductor. Especially, the influence of the layer of vernix caseosa, a fatty layer that covers the fetus, was investigated. The computations showed that the layer of vernix caseosa will affect the waveform of the fMCG. The signal processing procedure used is also discussed. It turned out to be difficult to deduce the onset and offset of the T-wave from the resulting averaged signals. Possibly, the QRS-complex does not provide a correct trigger to obtain a distinguishable T-wave in the averaged signal, because the RT-interval may be variable. (C) 1998 Elsevier Science S.A. All rights-reserved.
引用
收藏
页码:273 / 281
页数:9
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