Effects of electrode size and spacing on the resolution of intracardiac electrograms

被引:34
作者
Stinnett-Donnelly, Justin M. [1 ,2 ]
Thompson, Nathaniel [1 ,2 ]
Habel, Nicole [1 ]
Petrov-Kondratov, Vadim [1 ]
de Sa, Daniel D. Correa [1 ,2 ]
Bates, Jason H. T. [1 ,3 ,4 ]
Spector, Peter S. [1 ,2 ,4 ]
机构
[1] Univ Vermont, Coll Med, Dept Med, Burlington, VT 05405 USA
[2] Fletcher Allen Hlth Care, Burlington, VT 05405 USA
[3] Univ Vermont, Coll Engn & Comp Sci, Burlington, VT USA
[4] Cardiovasc Res Inst, Burlington, VT USA
基金
美国国家卫生研究院;
关键词
atrial fibrillation; computational model; electric potential; fractionated electrogram; unipolar and bipolar recordings; ATRIAL-FIBRILLATION; EXCITATION;
D O I
10.1097/MCA.0b013e3283507a9b
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Electrogram fractionation can result when multiple groups of cardiac cells are excited asynchronously within the recording region of a mapping electrode. The spatial resolution of an electrode thus plays an important role in mapping complex rhythms. Methods We used a computational model, validated against experimental measurements in vitro, to determine how spatial resolution is affected by electrode diameter, electrode length, interelectrode distance (in the case of bipolar recordings), and height of the electrode above a dipole current source. Results We found that increases in all these quantities caused progressive degradation in two independent measures of spatial resolution, with the strongest effect being due to changes in height above the tissue. Conclusion Our calculations suggest that if electrodes could be constructed to have negligible dimensions compared with those in use today, we would increase resolution by about one order of magnitude at most. Coron Artery Dis 23:126-132 (C) 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins.
引用
收藏
页码:126 / 132
页数:7
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