The centrosome is a polyfunctional multiprotein cell complex

被引:14
作者
Alieva, I. B. [1 ]
Uzbekov, R. E. [1 ,2 ]
机构
[1] Moscow MV Lomonosov State Univ, Belozersky Inst Phys Chem Biol, Moscow 119992, Russia
[2] Moscow MV Lomonosov State Univ, Fac Bioengn & Bioinformat, Moscow 119992, Russia
基金
俄罗斯基础研究基金会;
关键词
proteins; centrosome; centriole; microtubules; cell cycle;
D O I
10.1134/S0006297908060023
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
Contemporary knowledge about centrosome proteins and their ensembles, which can be divided into several functional groups-microtubule-nucleating proteins, microtubule-anchoring proteins, centriole-duplication proteins, cell cycle control proteins, primary cilia growth regulation proteins, and proteins of regulation of cytokinesis-is reviewed. Structural-temporal classification of centrosomal proteins and the scheme of interconnection between the different centrosomal protein complexes are presented.
引用
收藏
页码:626 / 643
页数:18
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