WebQTL - Web-based complex trait analysis

被引:233
作者
Wang, JT
Williams, RW
Manly, KF [1 ]
机构
[1] Roswell Pk Canc Inst, Dept Mol & Cellular Biol, Buffalo, NY 14263 USA
[2] Univ Tennessee, Ctr Hlth Sci, Dept Anat & Neurobiol, Ctr Genomics & Bioinformat, Memphis, TN 38163 USA
关键词
D O I
10.1385/NI:1:4:299
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
WebQTL is a website that combines databases of complex traits with fast software for mapping quantitative trait loci (QTLs) and for searching for correlations among traits. WebQTL also includes well-curated genotype data for five sets of mouse recombinant inbred (RI) lines. Thus, to identify QTLs, users need provide only quantitative trait data from one of the supported populations. The WebQTL databases include both biological traits-neuroanatomical, pharmacological, and behavioral traits-and microarray-based gene expression data from BXD RI lines. A search function finds correlations between RNA expression and biological traits, and mapping functions find QTLs for either type of trait. The WebQTL service is available at http://www.webqtl.org/.
引用
收藏
页码:299 / 308
页数:10
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