Periventricular leukomalacia causes visual impairment in preterm children - A study on the aetiologies of visual impairment in a population-based group of preterm children born 1989-95 in the county of Varmland, Sweden

Purpose: To determine the causes of visual impairment in a population-based group of visually impaired preterm children. Methods: Ophthalmological examination and magnetic resonance imaging or computed tomography of the brain were performed in all visually impaired preterm children born 1989-95 in Varmland. Results: Ten of 18 children had periventricular leukomalacia affecting the optic radiation, six had other lesions or malformations in the posterior visual pathways/cortex, but no child had visually impairing retinopathy of prematurity. Conclusion: We conclude that cerebral lesions or malformations are common causes of the visual functional deficit in visually impaired children born preterm. Brain damage should be suspected in a prematurely born child who presents with either of the signs: fixation difficulties, strabismus or nystagmus.