Sex chromosomes: Evolving dosage compensation

被引：10

作者：

Charlesworth, B ^{[1
]}

机构：

[1] Univ Edinburgh, Inst Cell Anim & Populat Biol, Ashworth Labs, Edinburgh EH9 2BR, Midlothian, Scotland

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 25期

关键词：

D O I：

10.1016/S0960-9822(98)00013-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dosage compensation of some X-linked genes varies among mammals. Inactivation of an X-linked copy of a gene in females appears to correlate with lack of an active homologue on the Y chromosome, implying that dosage compensation evolves in response to the loss of function of genes on the Y.

引用

收藏

页码：R931 / R933

页数：3

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