Getting pharmaceutical R&D back on target

被引：180

作者：

Bunnage, Mark E. ^{[1
]}

机构：

[1] Pfizer Labs, Med Chem, Sandwich, Kent, England

来源：

NATURE CHEMICAL BIOLOGY | 2011年 / 7卷 / 06期

关键词：

DRUG DISCOVERY; PROTEIN; INTERACTOME; SYSTEM; SIZE;

D O I：

10.1038/nchembio.581

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The pharmaceutical industry is in a period of crisis due to the low number of new drug approvals relative to the high levels of R&D investment. It is argued here that improving the quality of target selection is the single most important factor to transform industry productivity and bring innovative new medicines to patients.

引用

页码：335 / 339

页数：5

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