Prostate Cancer and Vitamin D: What Does the Evidence Really Suggest?

被引:7
作者
Barnett, Christine M. [1 ]
Beer, Tomasz M. [1 ]
机构
[1] Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol & Med Oncol, Portland, OR 97239 USA
关键词
Prostate cancer; Vitamin D; Supplementation; UV; HIGH-DOSE CALCITRIOL; D RESPONSE ELEMENT; CELL-LINE LNCAP; DAIRY-PRODUCTS; UNITED-STATES; 1,25-DIHYDROXYVITAMIN D-3; SUBSEQUENT DEVELOPMENT; ULTRAVIOLET-RADIATION; GENE POLYMORPHISMS; CALCIUM INTAKE;
D O I
10.1016/j.ucl.2011.04.007
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The optimal approach to vitamin D supplementation for the average healthy person is debatable. In patients with cancer, the role of vitamin D supplementation, possibly in treatment, is even less clear. Vitamin D is shown to play a role in prostate cancer biology; however, the clinical data have not consistently demonstrated a link. Additional studies are needed to determine if higher doses of vitamin D supplements could benefit selected populations (ie, the elderly or patients with cancer) even if they may not be beneficial for the general population.
引用
收藏
页码:333 / +
页数:11
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