HIV vaccine design and the neutralizing antibody problem

被引：635

作者：

Burton, DR

Desrosiers, RC

Doms, RW

Koff, WC

Kwong, PD

Moore, JP

Nabel, GJ

Sodroski, J

Wilson, IA

Wyatt, RT

机构：

[1] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA

[3] Harvard Univ, New England Reg Primate Res Ctr, Sch Med, Div Microbiol, Southborough, MA 01772 USA

[4] Univ Penn, Dept Pathol, Philadelphia, PA 19104 USA

[5] Int AIDS Vaccine Initiat, New York, NY USA

[6] NIH, Vaccine Res Ctr, Bethesda, MD 20892 USA

[7] Cornell Univ, Weill Med Ctr, Dept Microbiol & Immunol, New York, NY USA

[8] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Canc Immunol & AIDS, Boston, MA 02115 USA

[9] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

NATURE IMMUNOLOGY | 2004年 / 5卷 / 03期

关键词：

D O I：

10.1038/ni0304-233

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Eliciting broadly neutralizing antibodies to human immunodeficiency virus could bring closer the goal of a successful AIDS vaccine. Here the International AIDS Vaccine Initiative Neutralizing Antibody Consortium discusses current approaches to overcome the problems faced.

引用

页码：233 / 236

页数：4

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