Detection of intermolecular chemical exchange through decorrelation of two-spin order

被引：33

作者：

Skrynnikov, NR ^{[1
]}

Ernst, RR ^{[1
]}

机构：

[1] ETH Zentrum, Chem Phys Lab, CH-8092 Zurich, Switzerland

来源：

JOURNAL OF MAGNETIC RESONANCE | 1999年 / 137卷 / 01期

基金：

加拿大自然科学与工程研究理事会;

关键词：

intermolecular chemical exchange; decorrelation; multispin order; multiquantum coherence; L-tryptophan; amide proton exchange; HMQC;

D O I：

10.1006/jmre.1998.1666

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An initial correlation between two spins is lost when they are separated by intermolecular chemical exchange. This effect, termed "decorrelation by chemical exchange," manifests itself in a decay of the corresponding two-spin modes, It can be used for monitoring intermolecular chemical exchange, as is demonstrated for L-tryptophan where the decay of (HN)-H-1-N-15 two-spin order provides information on the exchange of indole protons with solvent water. (C) 1999 Academic Press.

引用

页码：276 / 280

页数：5

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