A novel chiral ruthenium porphyrin as highly efficient and selective catalyst for asymmetric cyclopropanations

被引：109

作者：

Frauenkron, M ^{[1
]}

Berkessel, A ^{[1
]}

机构：

[1] UNIV COLOGNE,INST ORGAN CHEM,D-50939 COLOGNE,GERMANY

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(97)01763-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantiomerically pure ruthenium carbonyl porphyrin 5 is an extremely active and selective catalyst for the asymmetric cyclopropanation of olefins with diazo compounds. At a catalyst loading of only 0.15 mol-%, quantitative yields, excellent diastereoselectivities (trans:cis 96:4) and high enantiomeric excesses (up to 91 %) of the product cyclopropanes were achieved in the reaction of styrene with ethyl diazoacetate. (C) 1997 Elsevier Science Ltd.

引用

页码：7175 / 7176

页数：2

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