Isolation and structural identification of bifidogenic growth stimulator produced by Propionibacterium freudenreichii

被引：70

作者：

Mori, H

Sato, Y

Taketomo, N

Kamiyama, T

Yoshiyama, Y

Meguro, S

Sato, H

Kaneko, T

机构：

[1] MEIJI MILK PROD CO,CENT RES INST,TOKYO 189,JAPAN

[2] MEIJI MILK PROD CO,HLTH SCI RES INST,KANAGAWA 250,JAPAN

来源：

JOURNAL OF DAIRY SCIENCE | 1997年 / 80卷 / 09期

关键词：

bifidogenic growth stimulator; Propionibacterium freudenreichii; 2-amino-3-carboxy-1,4-naphthoquinone;

D O I：

10.3168/jds.S0022-0302(97)76138-1

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

A bifidogenic growth stimulator produced by Propionibacterium freudenreichii was purified, and its chemical structure was determined. We obtained 7.1 mg of a bifidogenic growth stimulator from 1738 g of lyophilized P. freudenreichii cells by silica gel column chromatography, Sephadex LH-20 column chromatography, and preparative HPLC. The mass of the bifidogenic growth stimulator was 217.037 (C11H7NO4) as determined by high resolution mass spectrometry. Various experimental analyses indicated that the chemical structure of the bifidogenic growth stimulator was 2-amino-3-carboxy-1,4-naphthoquinone.

引用

页码：1959 / 1964

页数：6

共 18 条

[1]

AMEYAMA M, 1984, AGR BIOL CHEM TOKYO, V49, P699

[2]

[Anonymous], 1984, Bald Micro

[3]

Benno Y., 1987, Bifidobacteria and Microflora, V6, P59

[4] BIFIDOBACTERIA IN INTESTINAL-TRACT OF INFANTS - INVIVO STUDY [J].