Peripheral neuropathy in two patients with rheumatoid arthritis receiving infliximab treatment

被引：49

作者：

Tektonidou, Maria G. ^{[1
]}

Serelis, John ^{[1
]}

Skopouli, Fotini N. ^{[1
]}

机构：

[1] Euroclin Hosp, Dept Internal Med, Athens 11521, Greece

来源：

CLINICAL RHEUMATOLOGY | 2007年 / 26卷 / 02期

关键词：

adverse events; infliximab; peripheral neuropathy;

D O I：

10.1007/s10067-006-0317-z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Antitumor necrosis alpha agents have been successfully used for the treatment of rheumatoid and seronegative arthritis, Crohn's disease, psoriasis, and severe cases of vasculitis. Several side effects have been observed in patients receiving these agents including hypersensitivity reactions, infections, drug-induced lupus, or demyelinating syndromes. The presence of peripheral neuropathy has been reported only in isolated cases. We describe two cases of peripheral neuropathy which occurred in patients with rheumatoid arthritis receiving infliximab treatment, one with multifocal motor neuropathy with conduction block and another with axonal sensory polyneuropathy, reversed upon discontinuation of infliximab and intravenous gammaglobulin treatment.

引用

页码：258 / 260

页数：3

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