Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension

被引：42

作者：

Bond, Jonathan ^{[1
,2
]}

Gale, Daniel P. ^{[3
,4
]}

Connor, Thomas ^{[3
]}

Adams, Stuart

de Boer, Jasper ^{[5
]}

Gascoyne, Duncan M. ^{[5
,6
]}

Williams, Owen ^{[5
]}

Maxwell, Patrick H. ^{[3
]}

Ancliff, Philip J. ^{[5
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, MRC Clin Sci Ctr, London W12 0NN, England

[2] UCL, Great Ormond St Hosp Children, Mol Haematol & Canc Biol Unit, Inst Child Hlth,Dept Haematol, London, England

[3] UCL, Rayne Inst, Div Med, London, England

[4] Univ London Imperial Coll Sci Technol & Med, Kidney & Transplant Unit, London W12 0NN, England

[5] UCL, Inst Child Hlth, Mol Haematol & Canc Biol Unit, London, England

[6] Univ Oxford, Nuffield Dept Clin Lab Sci, Oxford, England

来源：

BLOOD | 2011年 / 117卷 / 13期

基金：

英国医学研究理事会;

关键词：

CHUVASH POLYCYTHEMIA; OXYGEN HOMEOSTASIS;

D O I：

10.1182/blood-2010-12-327569

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页码：3699 / 3701

页数：5

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