Importance of left atrial diameter and atrial fibrillatory frequency for conversion of persistent atrial fibrillation with oral flecainide

被引：40

作者：

Bollmann, A ^{[1
]}

Binias, KH ^{[1
]}

Toepffer, I ^{[1
]}

Molling, J ^{[1
]}

Geller, C ^{[1
]}

Klein, HU ^{[1
]}

机构：

[1] Univ Hosp Magdeburg, Dept Cardiol, D-39120 Magdeburg, Germany

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2002年 / 90卷 / 09期

关键词：

D O I：

10.1016/S0002-9149(02)02690-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study, determined the efficacy and safety of an oral flecainide-loading protocol (300-mg bolus followed by 200 to 300 mg/day) in 18 patients with no overt structural heart disease having atrial fibrillation (AF) of >24 hours in duration. Sinus rhythm was restored in 50% of patients,within a 72-hour observation period and was predicted by both echocardiographically determined left atrial diameter and fibrillatory frequency obtained from the surface electrocardiogram. Therefore, in patients with small left atria and/or a low fibrillatory frequency, a conversion attempt with oral flecainide may be warranted, irrespective of AF duration.

引用

页码：1011 / +

页数：5

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