SEOM clinical guidelines for anaplastic gliomas (2017)

被引:11
作者
Balana, C. [1 ]
Alonso, M. [2 ]
Hernandez, A. [3 ]
Perez-Segura, P. [4 ]
Pineda, E. [5 ]
Ramos, A. [3 ]
Sanchez, A. R. [6 ]
Teixidor, P. [7 ]
Verger, E. [5 ]
Benavides, M. [8 ]
机构
[1] Inst Catala Oncol Badalona, Ct Canyet S-N, Barcelona 08916, Spain
[2] Complejo Hosp Virgen del Rocio, Seville, Spain
[3] Hosp 12 Octubre, Madrid, Spain
[4] Hosp Univ Clin San Carlos, Madrid, Spain
[5] Hosp Clin Barcelona, Barcelona, Spain
[6] Complejo Asistencial Univ Leon, Leon, Spain
[7] Hosp Badalona Germans Trias & Pujol, Barcelona, Spain
[8] Hosp Univ Reg & Virgen de la Victoria, Malaga, Spain
关键词
Anaplastic glioma; Anaplastic astrocytoma; Anaplastic oligodendroglioma; HIGH-GRADE GLIOMAS; PHASE-III TRIAL; MALIGNANT GLIOMA; OLIGODENDROGLIOMA; CHEMOTHERAPY; RADIOTHERAPY; TEMOZOLOMIDE; OLIGOASTROCYTOMA; CLASSIFICATION; PROCARBAZINE;
D O I
10.1007/s12094-017-1762-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
The SEOM/GEINO clinical guidelines provide recommendations for radiological, and molecular diagnosis, treatment and follow-up of adult patients with anaplastic gliomas (AG). We followed the 2016 WHO classification which specifies the major diagnostic/prognostic and predictive value of IDH1/IDH2 missense mutations and 1p/19q codeletions in AG. The diagnosis of anaplastic oligoastrocytoma is discouraged. Surgery, radiotherapy and chemotherapy with PCV or TMZ are the first-line standard of care for AG with slight modifications according to molecular variables. A multidisciplinary team is highly recommended in the management of these tumors.
引用
收藏
页码:16 / 21
页数:6
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