Caspases:: more than just killers?

被引：153

作者：

Los, M ^{[1
]}

Stroh, C ^{[1
]}

Jänicke, RU ^{[1
]}

Engels, IH ^{[1
]}

Schulze-Osthoff, K ^{[1
]}

机构：

[1] Univ Munster, Dept Immunol & Cell Biol, D-48149 Munster, Germany

来源：

TRENDS IN IMMUNOLOGY | 2001年 / 22卷 / 01期

关键词：

D O I：

10.1016/S1471-4906(00)01814-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Proteases of the caspase family constitute the central executioners of apoptosis, Several recent observations suggest that caspases and apoptosis-regulatory molecules exert important functions beyond that of cell death, including the control of T-cell proliferation and cell-cycle progression. Here, Los and colleagues propose a model that directly connects cell suicide mechanisms to the regulation of cell-cycle progression.

引用

页码：31 / 34

页数：4

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