Quality of life considerations in gynecologic cancer

被引：102

作者：

Penson, Richard T.

Wenzel, Lari B.

Vergote, Ignace

Cella, David

机构：

[1] Univ Calif Irvine, Ctr Hlth Policy Res, Coll Med, Irvine, CA 92697 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

[3] Katholieke Univ Leuven Hosp, Dept Gynaecol Oncol, Louvain, Belgium

[4] Northwestern Univ, Evanston, IL USA

[5] Evanston NW Healthcare, Evanston, IL USA

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 2006年 / 95卷

关键词：

D O I：

10.1016/S0020-7292(06)60040-4

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Quality of life (QOL) is a fundamental consideration for patients with life threatening diseases. Major evolving paradigms are discussed: improved QOL with laparoscopic surgery, the impact on QOL of intraperitoneal chemotherapy for optimally cytoreduced ovarian cancer, combination therapy, sexuality, and survivorship. The goals of treatment for many patients with gynecologic tumors remain largely palliative, and patient reported QOL is the primary outcome determining the utility of treatment. Particularly in this area, QOL endpoints are increasingly important in clinical trials. The QOL issues facing gynecologic cancer patients, the use of validated QOL instruments, recent advances in the evaluation of interventions, and changes in concepts related to QOL are reviewed. (c) 2006 International Federation of Gynecology and Obstetrics. Published by Elsevier Science Ltd. All rights reserved.

引用

页码：S247 / S257

页数：11

共 91 条

[1] THE EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER QLQ-C30 - A QUALITY-OF-LIFE INSTRUMENT FOR USE IN INTERNATIONAL CLINICAL-TRIALS IN ONCOLOGY [J].