Contractile stress generation by actomyosin gels

被引：41

作者：

Carlsson, A. E. ^{[1
]}

机构：

[1] Washington Univ, Dept Phys, St Louis, MO 63130 USA

来源：

PHYSICAL REVIEW E | 2006年 / 74卷 / 05期

关键词：

D O I：

10.1103/PhysRevE.74.051912

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

The tension generated by randomly distributed myosin minifilaments in an actin gel is evaluated using a rigorous theorem relating the surface forces acting on the gel to the forces exerted by the myosins. The maximum tension generated per myosin depends strongly on the lengths of the myosin minifilaments and the actin filaments. The result is used to place an upper bound on the tension that can be generated during cytokinesis. It is found that actomyosin contraction by itself generates too little force for ring contraction during cytokinesis unless the actin filaments are tightly crosslinked into inextensible units much longer than a single actin filament.

引用

页数：6

共 34 条

[1] The tubulin ancester, FtsZ, draughtsman, designer and driving force for bacterial cytokinesis [J].