Ethnopharmacology and malaria: New hypothetical leads or old efficient antimalarials?

被引：45

作者：

Bourdy, G. ^{[1
]}

Willcox, M. L. ^{[2
]}

Ginsburg, H. ^{[3
]}

Rasoanaivo, Ph. ^{[4
]}

Graz, B. ^{[5
]}

Deharo, E. ^{[1
]}

机构：

[1] Univ Toulouse 3, UMR 152, IRD, Lab Pharmacochim Substances Nat & Pharmcophores R, Lima 18, Peru

[2] Res Initiat Tradit Antimalarial Methods, Buckingham MK18, England

[3] Hebrew Univ Jerusalem, Inst Life Sci, Dept Biol Chem, IL-91904 Jerusalem, Israel

[4] Inst Malgache Rech Appliques, Lab Phytochim & Pharmacol Cellular & Parasite, Antananarivo, Madagascar

[5] Antenna Technologies, CH-1202 Geneva, Switzerland

来源：

INTERNATIONAL JOURNAL FOR PARASITOLOGY | 2008年 / 38卷 / 01期

关键词：

ethnopharmacology; malaria; traditional treatment; medicinal plant; alternative medicine; Plasmodium;

D O I：

10.1016/j.ijpara.2007.07.004

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

New treatments are urgently needed to curb and eradicate malaria in developing countries. As most people living in malarial endemic areas use traditional medicine to fight this disease, why have new treatments not emerged recently from ethnopharmacology-oriented research? The rationale and limitations of the ethnopharmacological approach are discussed in this paper, focusing on ethnopharmacology methodologies and techniques used for assessing botanical samples for their antimalarial properties. Discrepancies often observed between strong ethnopharmacological reputation and laboratory results are discussed, as well as new research perspectives. (c) 2007 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.

引用

页码：33 / 41

页数：9

共 57 条

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