Comparative value of tissue Doppler imaging and m-mode color Doppler mitral flow propagation velocity for the evaluation of left ventricular filling pressure

被引:35
作者
Kidawa, M
Coignard, L
Drobinski, G
Krzeminska-Pakula, M
Thomas, D
Komajda, M
Isnard, R
机构
[1] Med Univ Lodz, Dept Cardiol, PL-91347 Lodz, Poland
[2] Hop La Pitie Salpetriere, Inst Cardiol, Paris, France
关键词
diastole; echocardiography; pressure; tissue Doppler;
D O I
10.1378/chest.128.4.2544
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: Recently, two new indexes based on the ratio of transmitral early diastolic velocity (E) to tissue Doppler imaging (TDI), and early diastolic velocity of mitral annulus (E') and E to propagation velocity (Vp) have been proposed to predict left ventricular (LV) filling pressures. However, little is known about the comparative value of these two indexes. Methods: We studied 71 consecutive patients referred for coronary angiography (mean age +/- SD, 65 + 11 years; 21 patients with LV ejection fraction [EF] < 50%). Complete Doppler echocardiographic examination including TDI and Vp measurements and direct measurement of LV end-diastolic pressure (LVEDP) were performed simultaneously in the catheterization laboratory. LV filling pressures were considered elevated when LVEDP was >= 15 mm Hg. Results: The correlation coefficients between E/E' and E/Vp and LVEDP were 0.68 (p = 0.01) and 0.54 (p = 0.01), respectively, in the overall population. The correlations were better in patients with low LV EF (< 50%) [0.8 (p = 0.01) and 0.77(p = 0.01)] and poor in patients with normal LV EF (0.57 [p = 0.05] and 0.41 [not significant]), respectively. Moreover, Vp measurements had higher interobserver variability compared to E' (14% vs 7%). The cutoff values for both indexes giving the best sensitivity and specificity in identifying LVEDP >= 15 mm Hg were 9 for (E/E') and 2 for (E/Vp) Conclusion: Both E/E' and E/Vp can be used for the evaluation of LV filling pressures. However, the sensitivity of these indexes, especially E/Vp, is hampered by EF. E/E' has a lower variability than Vp and should be preferred for estimation of filling pressures especially in patients with EF > 50%.
引用
收藏
页码:2544 / 2550
页数:7
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