Horizontal Transmission of Mutans Streptococci in Children

被引：26

作者：

Domejean, S. ^{[2
]}

Zhan, L. ^{[1
]}

DenBesten, P. K. ^{[3
]}

Stamper, J. ^{[4
]}

Boyce, W. T. ^{[4
,5
]}

Featherstone, J. D. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Prevent & Restorat Dent Sci, San Francisco, CA 94143 USA

[2] CHU, EA3847, Fac Odontol, Clermont Ferrand, France

[3] Univ Calif San Francisco, Dept Orofacial Sci, San Francisco, CA 94143 USA

[4] Univ Calif Berkeley, Berkeley, CA 94720 USA

[5] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada

来源：

JOURNAL OF DENTAL RESEARCH | 2010年 / 89卷 / 01期

关键词：

horizontal transmission; diversity; mutans streptococci; children; POLYMERASE-CHAIN-REACTION; ARBITRARILY PRIMED PCR; GENOTYPIC DIVERSITY; CARIES-FREE; STRAINS; FAMILIES; COLONIZATION; PROFILES; SOBRINUS;

D O I：

10.1177/0022034509353400

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

It has not been established whether transmission of mutans streptococci occurs between unrelated children older than 4 years of age. The aim of the study was to investigate the possible transmission of mutans streptococci genotypes from child to child in kindergarten. We studied 96 children (ages 5-6 yrs) in three San Francisco Bay Area public schools. Mutans streptococci colonies from each child were isolated from selective culture on Mitis Salivarius Sucrose Bacitracin agar. We used arbitrary primed polymerase chain reactions to determine the mutans streptococci genotypes. Two children (not siblings) in each of the three schools (6%) shared an identical amplitype of S. mutans, unique to each pair. The 19 S. sobrinus amplitypes were found in 12 children, and all were unique to each child. The presence of matching genotypes of S. mutans demonstrates horizontal transmission of this species between unrelated children aged 5-6 years.

引用

页码：51 / 55

页数：5

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