Depression in the elderly: new concepts and therapeutic approaches

被引:33
作者
Mecocci, P [1 ]
Cherubini, A [1 ]
Mariani, E [1 ]
Ruggiero, C [1 ]
Senin, U [1 ]
机构
[1] Univ Perugia, Dept Clin & Expt Med, Sect Gerontol & Geriat, I-06122 Perugia, Italy
关键词
comorbidity; depression; disability; elderly; mortality; quality of life; treatment of depression;
D O I
10.1007/BF03327382
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 [法学]; 0303 [社会学]; 100203 [老年医学];
摘要
Depression is one of the leading causes of suffering in the elderly, but it is often under-diagnosed and under-treated, partly due to the false belief that depression is a common aspect of aging. Depression in the elderly is frequently comorbid with medical illnesses, may often be expressed by somatic complaints, and may be a risk factor for other diseases such as dementia and coronary artery disease. Depression decreases the quality of life and increases disability and the risk of mortality, also due to suicide. Although several effective antidepressant drugs are available, with a favorable therapeutic index, non-pharmacological treatments, such as psychotherapy and exercise, should receive greater attention, since combination therapy is probably more effective. (C)2004, Editrice Kurtis.
引用
收藏
页码:176 / 189
页数:14
相关论文
共 236 条
[1]
Abas M, 2002, BRIT J PSYCHIAT, V181, P123
[2]
Alexopoulos G S, 2001, Postgrad Med, VSpec No Pharmacotherapy, P1
[3]
Alexopoulos GS, 1997, ARCH GEN PSYCHIAT, V54, P915
[4]
Clinical presentation of the "depression-executive dysfunction syndrome" of late life [J].
Alexopoulos, GS ;
Kiosses, DN ;
Klimstra, S ;
Kalayam, B ;
Bruce, ML .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2002, 10 (01) :98-106
[5]
Comorbidity of late life depression: An opportunity for research on mechanisms and treatment [J].
Alexopoulos, GS ;
Buckwalter, K ;
Olin, J ;
Martinez, R ;
Wainscott, C ;
Krishnan, KRR .
BIOLOGICAL PSYCHIATRY, 2002, 52 (06) :543-558
[6]
BRAIN COMPUTED-TOMOGRAPHY FINDINGS IN GERIATRIC DEPRESSION AND PRIMARY DEGENERATIVE DEMENTIA [J].
ALEXOPOULOS, GS ;
YOUNG, RC ;
SHINDLEDECKER, RD .
BIOLOGICAL PSYCHIATRY, 1992, 31 (06) :591-599
[7]
ALEXOPOULOS GS, 2000, CLIN GERIATR MED, V8, P69
[8]
Long-term treatment of geropsychiatric depressed patients with venlafaxine [J].
Amore, M ;
Ricci, M ;
Zanardi, R ;
Perez, J ;
Ferrari, G .
JOURNAL OF AFFECTIVE DISORDERS, 1997, 46 (03) :293-296
[9]
Treating depression in old age: the reasons to be positive [J].
Anderson, DN .
AGE AND AGEING, 2001, 30 (01) :13-17
[10]
The prevalence of comorbid depression in adults with diabetes - A meta-analysis [J].
Anderson, RJ ;
Freedland, KE ;
Clouse, RE ;
Lustman, PJ .
DIABETES CARE, 2001, 24 (06) :1069-1078