Comparison of calcium alginate film with collagen membrane for guided bone regeneration in mandibular defects in rabbits

被引:37
作者
Huang, JQ [1 ]
He, H [1 ]
Sheng, LP [1 ]
Gu, GH [1 ]
机构
[1] Zhe Jiang Univ, Affiliated Hosp 2, Coll Med, Dept Oral & Maxillofacial Surg, Hangzhou 310009, Peoples R China
关键词
D O I
10.1053/joms.2002.36108
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Purpose: We sought to compare calcium alginate film (CAT) with collagen membrane (CM) regarding their effects on guided bone regeneration. Materials and Methods: Circular bone defects with 5-mm diameter were created in the region anterior to both mandibular angles in 34 rabbits. The defects on one side were covered with a CAF, and the contralateral side with CM. Heating condition was analyzed with gross, radiographic, electromicroscopic, histologic, and immunohistochemical studies and image pattern analysis system after 1, 2, 4, 6, and 8 weeks. Results: CM absorbed more slowly but collected fewer osteoinductive factors (P < .05) in the early period. CAF induced dense bone formation, whereas CM produced less newly formed bone. Conclusion: CAF is more efficacious than CM in guided bone regeneration in this animal model. (C) 2002 American Association of Oral and Maxillofacial Surgeons.
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收藏
页码:1449 / 1454
页数:6
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