Simple synthesis of benzofuranoid neolignans from Myristica fragrans

被引：36

作者：

Juhász, L ^{[1
]}

Kürti, L ^{[1
]}

Antus, S ^{[1
]}

机构：

[1] Univ Debrecen, Dept Organ Chem, H-4010 Debrecen, Hungary

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 06期

关键词：

D O I：

10.1021/np990327h

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The total synthesis of four neolignans-fragnasols A (1), B (2), and C (3) and dehydrodiisoeugenol (4)-starting from the readily available phenol derivative isoeugenol (5) was accomplished. The key step of the synthesis of these natural products is a novel type of dimerization of 5 into 4 with iodobenzene diacetate.

引用

页码：866 / 870

页数：5

共 21 条

[1]

ANTUS S, 1978, LIEBIGS ANN CHEM, P107

[2]

ANTUS S, 1987, LIEBIGS ANN CHEM, P357

[3]

ANTUS S, 1989, LIEBIGS ANN CHEM, P593

[4]

ANTUS S, 1990, LIEBIGS ANN CHEM, P495

[5] METHOD FOR THE CLEAVAGE OF OSMATE ESTERS [J].

BARAN, JS .

JOURNAL OF ORGANIC CHEMISTRY, 1960, 25 (02) :257-257

[6]

FUKUYAMA Y, 1986, PLANTA MED, P502

[7] CONSTITUENTS OF MACE .3. NEW NEOLIGNANS AND LIGNANS FROM THE ARIL OF MYRISTICA-FRAGRANS [J].

HADA, S ;

HATTORI, M ;

TEZUKA, Y ;

KIKUCHI, T ;

NAMBA, T .

PHYTOCHEMISTRY, 1988, 27 (02) :563-568

[8]

HATTORI M, 1986, CHEM PHARM BULL, V34, P3885

[9]

HATTORI M, 1988, CHEM PHARM BULL, V36, P648

[10]

HERCOUET A, 1979, TETRAHEDRON LETT, P2995

← 1 2 3 →