Environmental factors in Crohn's disease

被引:1
作者
Cosnes, J. [1 ]
Seksik, Ph. [1 ]
机构
[1] Hop St Antoine, Serv Gastroenterol & Nutr, F-75571 Paris 12, France
关键词
appendectomy; Crohn's disease; smoking;
D O I
10.1007/BF03018510
中图分类号
R61 [外科手术学];
学科分类号
摘要
The most important environmental factor recognized in Crohn's disease is cigarette smoking. Smoking increases the risk of Crohn's disease and worsens considerably the course of the disease. Conversely, smoking cessation is followed rapidly by reversal of the effect. Persuading patients to stop smoking is probably the most cost-effective strategy for controlling disease activity. The contraceptive pill and appendectomy have no effect. The role of other environmental factors remains putative although dietary factors, which are the most difficult to study, may be important.
引用
收藏
页码:679 / 688
页数:10
相关论文
共 88 条
[1]
Appendectomy is followed by increased risk of Crohn's disease [J].
Andersson, RE ;
Olaison, G ;
Tysk, C ;
Ekbom, A .
GASTROENTEROLOGY, 2003, 124 (01) :40-46
[2]
Environmental risk factors in paediatric inflammatory bowel diseases: a population based case control study [J].
Baron, S ;
Turck, D ;
Leplat, C ;
Merle, V ;
Gower-Rousseau, C ;
Marti, R ;
Yzet, T ;
Lerebours, E ;
Dupas, JL ;
Debeugny, S ;
Salomez, JL ;
Cortot, A ;
Colombel, JF .
GUT, 2005, 54 (03) :357-363
[3]
BREAST-FEEDING DURING INFANCY IN PATIENTS WHO LATER DEVELOP CROHNS-DISEASE [J].
BERGSTRAND, O ;
HELLERS, G .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1983, 18 (07) :903-906
[4]
Inflammatory bowel disease in Iceland, 1990-1994:: a prospective, nationwide, epidemiological study [J].
Björnsson, S ;
Jóhannsson, JH .
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2000, 12 (01) :31-38
[5]
INCREASED RISK OF INFLAMMATORY BOWEL-DISEASE ASSOCIATED WITH ORAL-CONTRACEPTIVE USE [J].
BOYKO, EJ ;
THEIS, MK ;
VAUGHAN, TL ;
NICOLBLADES, B .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1994, 140 (03) :268-278
[6]
Defining complex contributions of NOD2/CARD15 gene mutations, age at onset, and tobacco use on Crohn's disease phenotypes [J].
Brant, SR ;
Picco, MF ;
Achkar, JP ;
Bayless, TM ;
Kane, SV ;
Brzezinski, A ;
Nouvet, FJ ;
Bonen, D ;
Karban, A ;
Dassopoulos, T ;
Karaliukas, R ;
Beaty, TH ;
Hanauer, SB ;
Duerr, RH ;
Cho, JH .
INFLAMMATORY BOWEL DISEASES, 2003, 9 (05) :281-289
[7]
Effect of cigarette smoking on the course of Crohn's disease [J].
BreuerKatschinski, BD ;
Hollander, N ;
Goebell, H .
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 1996, 8 (03) :225-228
[8]
In siblings with similar genetic susceptibility for inflammatory bowel disease, smokers tend to develop Crohn's disease and non-smokers develop ulcerative colitis [J].
Bridger, S ;
Lee, JCW ;
Bjarnason, I ;
Jones, JEL ;
Macpherson, AJ .
GUT, 2002, 51 (01) :21-25
[9]
A META-ANALYSIS OF THE ROLE OF SMOKING IN INFLAMMATORY BOWEL-DISEASE [J].
CALKINS, BM .
DIGESTIVE DISEASES AND SCIENCES, 1989, 34 (12) :1841-1854
[10]
Risk of inflammatory bowel disease attributable to smoking, oral contraception and breastfeeding in Italy:: a nationwide case-control study [J].
Corrao, G ;
Tragnone, A ;
Caprilli, R ;
Trallori, G ;
Papi, C ;
Andreoli, A ;
Di Paolo, M ;
Riegler, G ;
Rigo, GP ;
Ferraù, O ;
Mansi, C ;
Ingrosso, M ;
Valpiani, D .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 1998, 27 (03) :397-404