An adaptive radiation model for the origin of new gene functions

被引:141
作者
Francino, MP
机构
[1] Lawrence Berkeley Natl Lab, DOE Joint Genome Inst, Evolutionary Genom Dept, Walnut Creek, CA 94598 USA
[2] Lawrence Berkeley Natl Lab, Genom Div, Walnut Creek, CA USA
关键词
D O I
10.1038/ng1579
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Current models for the evolution of new gene functions after gene duplication presume that the duplication events themselves have no effect on fitness. But those duplications that result in new gene functions are likely to be positively selected from their inception. The evolution of new function may start with the amplification of an existing gene with some level of preadaptation for that function, followed by a period of competitive evolution among the gene copies, resulting in the preservation of the most effective variant and the 'pseudogenization' and eventual loss of the rest.
引用
收藏
页码:573 / 577
页数:5
相关论文
共 60 条
[1]   The 'evolvability' of promiscuous protein functions [J].
Aharoni, A ;
Gaidukov, L ;
Khersonsky, O ;
Gould, SM ;
Roodveldt, C ;
Tawfik, DS .
NATURE GENETICS, 2005, 37 (01) :73-76
[2]  
CAIRNS J, 1991, GENETICS, V128, P695
[3]   Whole-tree methods for detecting differential diversification rates [J].
Chan, KMA ;
Moore, BR .
SYSTEMATIC BIOLOGY, 2002, 51 (06) :855-865
[4]   Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios [J].
Clark, AG ;
Glanowski, S ;
Nielsen, R ;
Thomas, PD ;
Kejariwal, A ;
Todd, MA ;
Tanenbaum, DM ;
Civello, D ;
Lu, F ;
Murphy, B ;
Ferriera, S ;
Wang, G ;
Zheng, XG ;
White, TJ ;
Sninsky, JJ ;
Adams, MD ;
Cargill, M .
SCIENCE, 2003, 302 (5652) :1960-1963
[5]   Genome evolution in yeasts [J].
Dujon, B ;
Sherman, D ;
Fischer, G ;
Durrens, P ;
Casaregola, S ;
Lafontaine, I ;
de Montigny, J ;
Marck, C ;
Neuvéglise, C ;
Talla, E ;
Goffard, N ;
Frangeul, L ;
Aigle, M ;
Anthouard, V ;
Babour, A ;
Barbe, V ;
Barnay, S ;
Blanchin, S ;
Beckerich, JM ;
Beyne, E ;
Bleykasten, C ;
Boisramé, A ;
Boyer, J ;
Cattolico, L ;
Confanioleri, F ;
de Daruvar, A ;
Despons, L ;
Fabre, E ;
Fairhead, C ;
Ferry-Dumazet, H ;
Groppi, A ;
Hantraye, F ;
Hennequin, C ;
Jauniaux, N ;
Joyet, P ;
Kachouri, R ;
Kerrest, A ;
Koszul, R ;
Lemaire, M ;
Lesur, I ;
Ma, L ;
Muller, H ;
Nicaud, JM ;
Nikolski, M ;
Oztas, S ;
Ozier-Kalogeropoulos, O ;
Pellenz, S ;
Potier, S ;
Richard, GF ;
Straub, ML .
NATURE, 2004, 430 (6995) :35-44
[6]   Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae [J].
Dunham, MJ ;
Badrane, H ;
Ferea, T ;
Adams, J ;
Brown, PO ;
Rosenzweig, F ;
Botstein, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (25) :16144-16149
[7]  
Eldredge N., 1972, P82
[8]  
Force A, 1999, GENETICS, V151, P1531
[9]   Lineage-specific gene duplication and loss in human and great ape evolution [J].
Fortna, A ;
Kim, Y ;
MacLaren, E ;
Marshall, K ;
Hahn, G ;
Meltesen, L ;
Brenton, M ;
Hink, R ;
Burgers, S ;
Hernandez-Boussard, T ;
Karimpour-Fard, A ;
Glueck, D ;
McGavran, L ;
Berry, R ;
Pollack, J ;
Sikela, JM .
PLOS BIOLOGY, 2004, 2 (07) :937-954
[10]   Gene duplication and biased functional retention of paralogs in bacterial genomes [J].
Gevers, D ;
Vandepoele, K ;
Simillion, C ;
Van de Peer, Y .
TRENDS IN MICROBIOLOGY, 2004, 12 (04) :148-154