Campylobacter jejuni CsrA mediates oxidative stress responses, biofilm formation, and host cell invasion

被引：115

作者：

Fields, Joshua A. ^{[1
]}

Thompson, Stuart A. ^{[1
]}

机构：

[1] Med Coll Georgia, Dept Biochem & Mol Biol, Augusta, GA 30912 USA

来源：

JOURNAL OF BACTERIOLOGY | 2008年 / 190卷 / 09期

关键词：

D O I：

10.1128/JB.01928-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The putative global posttranscriptional regulator csrA was mutated in Campylobacter jejuni 81-176. The csrA mutant was attenuated in surviving oxidative stress. CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis.

引用

页码：3411 / 3416

页数：6

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