Protective effect of Lycium barbarum polysaccharides on oxidative damage in skeletal muscle of exhaustive exercise rats

被引：120

作者：

Niu, Ai-jun ^{[1
]}

Wu, Jing-mei ^{[2
]}

Yu, Ding-hai ^{[3
]}

Wang, Ru ^{[2
]}

机构：

[1] Guangzhou Sport Univ, Wushu Dept, Guangzhou 510500, Peoples R China

[2] Shanghai Univ Sport, Sch Sports Sci, Shanghai 200438, Peoples R China

[3] Shanghai Univ Sport, Sci Res Dept, Shanghai 200438, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2008年 / 42卷 / 05期

关键词：

exhaustive exercise; oxidative stress; Lycium barbarum polysaccharides;

D O I：

10.1016/j.ijbiomac.2008.02.003

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The aim of this study was to determine the modulatory effect of Lycium barbarum polysaccharicles (LBP) on the oxidative stress induced by an exhaustive exercise. 32 male Wistar rats were taken in the study. The experiment was a 30-day exhaustive exercise program. We determined the lipid peroxidation, glycogen levels, and anti-oxidant enzyme activities in skeletal muscle. The results demonstrated that L. barbarum polysaccharides administration significantly increases glycogen level and anti-oxidant enzyme activities, and decreased malondialdehyde (MDA) level and creatine kinase activities. In conclusion, L barbarum polysaccharides administration can significantly decrease the oxidative stress induced by the exhaustive exercise. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：447 / 449

页数：3

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