The Role of Diet and Nutrient Composition in Nonalcoholic Fatty Liver Disease

被引：130

作者：

McCarthy, Erin Marie ^{[2
]}

Rinella, Mary E. ^{[1
]}

机构：

[1] Northwestern Univ, NW Mem Hosp, Feinberg Sch Med, Dept Gastroenterol & Hepatol, Chicago, IL 60611 USA

[2] NW Fac Fdn, Chicago, IL USA

来源：

JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS | 2012年 / 112卷 / 03期

关键词：

Nutrition; Obesity; NAFLD/NASH; Fatty liver; ALANINE AMINOTRANSFERASE LEVELS; RANDOMIZED CONTROLLED-TRIAL; METABOLIC SYNDROME; WEIGHT-LOSS; VITAMIN-E; INSULIN-RESISTANCE; HEPATIC STEATOSIS; PHYSICAL-ACTIVITY; RISK-FACTORS; CARDIOVASCULAR-DISEASE;

D O I：

10.1016/j.jada.2011.10.007

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the developed world. NAFLD is tightly linked to insulin resistance and considered to be the hepatic manifestation of the metabolic syndrome. The cornerstone of any treatment regimen for patients with NAFLD is lifestyle modification focused on weight loss, exercise, and improving insulin sensitivity. Here we review the literature and discuss the role of diet and nutrient composition in the management of NAFLD. Because there are currently no specific dietary guidelines for NAFLD, this review proposes a dietary framework for patients with NAFLD based on the available evidence and extrapolates from dietary guidelines aimed at reducing insulin resistance and cardiovascular risk. J Acad Nutr Diet. 2012;112:401-409.

引用

页码：401 / 409

页数：9

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