Elevated levels of interleukin-2 receptor and intercellular adhesion molecule 1 in sera from a venezuelan cohort of patients with dengue

被引：12

作者：

Valero, N. ^{[1
]}

Larreal, Y. ^{[1
]}

Espina, L. M. ^{[1
]}

Reyes, I. ^{[1
]}

Maldonado, M. ^{[1
]}

Mosquera, J. ^{[2
]}

机构：

[1] Univ Zulia, Inst Invest Clin Dr Americo Negrette, Fac Med, Sect Virol, Zulia, Venezuela

[2] Univ Zulia, Inst Invest Clin Dr Americo Negrette, Fac Med, Sect Immunol & Biol Celular, Zulia, Venezuela

来源：

ARCHIVES OF VIROLOGY | 2008年 / 153卷 / 01期

关键词：

D O I：

10.1007/s00705-007-1080-4

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This study evaluated the levels of soluble interleukin-2 receptor (sIL-2R) and soluble intercellular adhesion molecule-1 (sICAM-1) in patients with dengue. Sera from 17 patients with dengue fever (DF), 15 with dengue hemorrhagic fever (DHF) and 12 healthy individuals were obtained. Increased levels of sIL-2R and sICAM-1 were found in patients with DF and DHF when compared to normal; those were not correlated with leukocytes, hepatic serum enzyme levels or haemostatic parameters. Levels of sIL-2R were related to the different grades of DHF. These results suggest that increased levels of sIL-2R and sICAM-1 are a common feature of dengue.

引用

页码：199 / 203

页数：5

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