Understanding methadone metabolism - A foundation for safer use

被引：6

作者：

Clark, J. David ^{[1
,2
]}

机构：

[1] Stanford Univ, Sch Med, Dept Anesthesia, Stanford, CA 94305 USA

[2] Vet Affairs Palo Alto Healthcare Syst, Palo Alto, CA USA

来源：

ANESTHESIOLOGY | 2008年 / 108卷 / 03期

关键词：

D O I：

10.1097/ALN.0b013e318164937c

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

引用

页码：351 / 352

页数：2

共 9 条

[1] Management of perioperative pain in patients chronically consuming opioids [J].

Carroll, IR ;

Angst, MS ;

Clark, JD .

REGIONAL ANESTHESIA AND PAIN MEDICINE, 2004, 29 (06) :576-591

[2] Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment [J].

Crettol, S ;

Déglon, JJ ;

Besson, J ;

Croquette-Krokkar, M ;

Gothuey, I ;

Hämmig, R ;

Monnat, M ;

Hüttemann, H ;

Baumann, P ;

Eap, CB .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2005, 78 (06) :593-604

[3] ABCB1 and cytochrome P450 genotypes and phenotypes:: Influence on methadone plasma levels and response to treatment [J].

Crettol, Severine ;

Deglon, Jean-Jacques ;

Besson, Jacques ;

Croquette-Krokar, Marina ;

Haemmig, Robert ;

Gothuey, Isabelle ;

Monnat, Martine ;

Eap, Chin B. .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2006, 80 (06) :668-681

[4] QTc prolongation and Torsades de Pointes associated with methadone therapy [J].

Routhier, Denise D. ;

Katz, Kenneth D. ;

Brooks, Daniel E. .

JOURNAL OF EMERGENCY MEDICINE, 2007, 32 (03) :275-278

[5] Surveillance of methadone-related adverse drug events using multiple public health data sources [J].

Sims, Shannon A. ;

Snow, Laverne A. ;

Porucznik, Christina A. .

JOURNAL OF BIOMEDICAL INFORMATICS, 2007, 40 (04) :382-389

[6]

Terpening Chris M, 2007, W V Med J, V103, P14

[7]

Toombs JD, 2005, AM FAM PHYSICIAN, V71, P1353

[8] Role of CYP2B6 in stereoselective human methadone metabolism [J].

Totah, Rheem A. ;

Sheffels, Pamela ;

Roberts, Toni ;

Whittington, Dale ;

Thummel, Kenneth ;

Kharasch, Evan D. .

ANESTHESIOLOGY, 2008, 108 (03) :363-374

[9] Polymorphic CYP2B6:: molecular mechanisms and emerging clinical significance [J].

Zanger, Ulrich M. ;

Klein, Kathrin ;

Saussele, Tanja ;

Blievernicht, Julia ;

Hofmann, Marco H. ;

Schwab, Matthias .

PHARMACOGENOMICS, 2007, 8 (07) :743-759

← 1 →