A correlation network approach to metabolic data analysis for tomato fruits

被引:60
作者
Ursem, Remco [1 ,2 ]
Tikunov, Yury [2 ,3 ]
Bovy, Arnaud [2 ,3 ]
van Berloo, Ralph [1 ,2 ]
van Eeuwijk, Fred [2 ,4 ]
机构
[1] Univ Wageningen & Res Ctr, Lab Plant Breeding, NL-6700 AJ Wageningen, Netherlands
[2] Ctr BioSyst Genom, NL-6700 AB Wageningen, Netherlands
[3] Plant Res Int, NL-6700 AA Wageningen, Netherlands
[4] Biometris, NL-6700 AC Wageningen, Netherlands
关键词
correlation network; metabolomics; network analysis; principal component analysis; tomato;
D O I
10.1007/s10681-008-9672-y
中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
Network analysis of correlations between abundances of metabolites across tomato genotypes can help in unraveling the biological basis of organoleptic variation in tomato. We illustrate how to construct and interpret simple correlations networks using metabolic data collected on a diverse set of tomato genotypes. Various types of correlations are calculated and displayed in the form of networks. Interpretations on the basis of network analyses are compared to interpretations following principal components analysis.
引用
收藏
页码:181 / 193
页数:13
相关论文
共 23 条
[1]   Flavor trivia and tomato aroma: Biochemistry and possible mechanisms for control of important aroma components [J].
Baldwin, EA ;
Scott, JW ;
Shewmaker, CK ;
Schuch, W .
HORTSCIENCE, 2000, 35 (06) :1013-1022
[2]   Effect of volatiles and their concentration on perception of tomato descriptors [J].
Baldwin, EA ;
Goodner, K ;
Plotto, A ;
Pritchett, K ;
Einstein, M .
JOURNAL OF FOOD SCIENCE, 2004, 69 (08) :S310-S318
[3]  
Batagelj V, 2004, MATH VIS, P77
[4]   CONTROLLING THE FALSE DISCOVERY RATE - A PRACTICAL AND POWERFUL APPROACH TO MULTIPLE TESTING [J].
BENJAMINI, Y ;
HOCHBERG, Y .
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY, 1995, 57 (01) :289-300
[5]  
BURDON RD, 1977, SILVAE GENET, V26, P168
[6]  
BUTTERY RG, 1993, ACS SYM SER, V525, P23
[7]   The origin of correlations in metabolomics data [J].
Camacho, Diogo ;
de la Fuente, Alberto ;
Mendes, Pedro .
METABOLOMICS, 2005, 1 (01) :53-63
[8]  
Dillon W.R., 1984, MULTIVARIATE ANAL ME
[9]  
FALCONER DS, 1996, ITNRO QUANTITATIVE G
[10]   Calibration of multivariate scatter plots for exploratory analysis of relations within and between sets of variables in genomic research [J].
Graffelman, J ;
van Eeuwijk, F .
BIOMETRICAL JOURNAL, 2005, 47 (06) :863-879