Postoperative Management of Crohn Disease

被引：17

作者：

Cho, Su Min ^{[2
]}

Cho, Sung W. ^{[3
]}

Regueiro, Miguel ^{[1
,4
,5
]}

机构：

[1] Univ Pittsburgh, Med Ctr, Gastroenterol Hepatol & Nutr Fellowship Training, Div Gastroenterol Hepatol & Nutr, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Med Ctr, Dept Gastroenterol Hepatol & Nutr, Pittsburgh, PA 15213 USA

[3] Univ Pittsburgh, Med Ctr, Dept Gen Surg, Pittsburgh, PA 15213 USA

[4] Univ Pittsburgh, Sch Med, Dept Med, Pittsburgh, PA 15213 USA

[5] Ctr Inflammatory Bowel Dis, Pittsburgh, PA 15213 USA

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2009年 / 38卷 / 04期

关键词：

Crohn disease; Postoperative; Prevention; 5-ASA; Immunomodulators; Infliximab; DOUBLE-BLIND; ENDOSCOPIC RECURRENCE; PREVENTION; MESALAMINE; PLACEBO; RESECTION; PROPHYLAXIS; MESALAZINE; RELAPSE; METRONIDAZOLE;

D O I：

10.1016/j.gtc.2009.07.008

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Crohn disease often recurs after surgical resection. Despite extensive research in the prevention of postoperative Crohn disease, optimal management strategies have yet to be defined. Risk of disease recurrence needs to be carefully balanced against potential risks associated with treatment. Patients with low risk of postoperative recurrence may not require medication, whereas those at moderate risk may benefit from antibiotics or immunomodulators. Those at highest risk of recurrence may benefit from biologic therapy for maintenance of surgical remission. Postoperative colonoscopy within 1 year of resective surgery is important for identification of disease recurrence and modification of medications.

引用

页码：753 / +

页数：11

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