H2-antagonists in the treatment of colon and breast cancer

被引：35

作者：

Bolton, E ^{[1
]}

King, J ^{[1
]}

Morris, DL ^{[1
]}

机构：

[1] Univ New S Wales, St George Hosp, Dept Surg, Sydney, NSW 2217, Australia

来源：

SEMINARS IN CANCER BIOLOGY | 2000年 / 10卷 / 01期

基金：

英国医学研究理事会;

关键词：

histamine; histamine antagonists; tumour infiltrating lymphocytes; cell-mediated immunity;

D O I：

10.1006/scbi.2000.0301

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Several clinical trials have now been carried out with histamine type 2 receptor antagonists in cancer patients often as an adjunct to surgical resection of the primary tumour. While promising results have been obtained in some groups of patients with gastrointestinal cancer, with increased survival and evidence of increased immunological recognition of tumour; results are less encouraging for breast cancer This may be due to differences in the levels of histamine or the role of histamine in growth of these different tumour types.

引用

页码：3 / 10

页数：8

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