The role of zinc in life: A review

被引：218

作者：

Frassinetti, Stefania ^{[1
]}

Bronzetti, Giorgio ^{[1
]}

Caltavuturo, Leonardo ^{[1
]}

Cini, Marco ^{[1
]}

Della Croce, Clara ^{[1
]}

机构：

[1] CNR, Inst Agr Biol & Biotechnol, Sect Pisa, I-56124 Pisa, Italy

来源：

JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY | 2006年 / 25卷 / 03期

关键词：

zinc; biovailability; toxicity; carcinogenicity; immunodeficiency; antioxidant;

D O I：

10.1615/JEnvironPatholToxicolOncol.v25.i3.40

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Zinc is a common element in human and natural environments and plays an important part in many biological processes. Zinc, which is defined as an "essential trace element," or a "micro-nutrient," is essential for the normal growth and the reproduction of all higher plants and animals, and of humans. In addition, it plays a key role during physiological growth and fulfills an immune function. It is vital for the functionality of more than 300 enzymes, for the stabilization of DNA, and for gene expression. This review summarizes the role and manifestations of zinc in the environment and its importance for human health and metabolism, as well as its physiological role. Toxicity, teratogenicity, carcinogenicity, and immunological functions of zinc are outlined with particular reference to the properties of zinc as an antioxidant, and its role in cancer prevention.

引用

页码：597 / 610

页数：14

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