Cerebral venous and sinus thrombosis with cerebrospinal fluid circulation block after the first methotrexate administration by lumbar puncture

被引：17

作者：

Bienfait, HP

Gijtenbeek, JMM

van den Bent, MJ

de Bruin, HG

Voogt, PJ

Pillay, M

机构：

[1] Acad Ziekenhuis Rotterdam, Daniel Hoed Klin, Dept Neurooncol, NL-3075 EA Rotterdam, Netherlands

[2] Acad Ziekenhuis Rotterdam, Daniel Hoed Klin, Dept Neurol, NL-3075 EA Rotterdam, Netherlands

[3] Acad Ziekenhuis Rotterdam, Daniel Hoed Klin, Dept Radiol, NL-3075 EA Rotterdam, Netherlands

[4] Acad Ziekenhuis Rotterdam, Daniel Hoed Klin, Dept Nucl Med, NL-3075 EA Rotterdam, Netherlands

[5] Acad Ziekenhuis Rotterdam, Daniel Hoed Klin, Dept Hematol, NL-3075 EA Rotterdam, Netherlands

来源：

NEURORADIOLOGY | 2002年 / 44卷 / 11期

关键词：

cerebral venous and sinus thrombosis (CVST); small lymphocytic lymphoma/leukemia; cerebrospinal fluid block; lumbar puncture; intrathecal methotrexate; cisternography;

D O I：

10.1007/s00234-002-0854-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report a patient treated for small lymphocytic lymphoma/leukemia with cerebral venous and sinus thrombosis (CVST) after lumbar puncture with intrathecal administration of methotrexate (MTX). He also developed a cerebrospinal fluid flow block. This is the first report of an association between lumbar puncture and intrathecally administered MTX and the development of CVST. Intrathecal treatment in this patient was discontinued and he was successfully treated with high-dose low-molecular-weight heparin subcutaneously.

引用

页码：929 / 932

页数：4

共 17 条

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