Cytokines: Shared receptors, distinct functions

被引：55

作者：

DiSanto, JP

机构：

来源：

CURRENT BIOLOGY | 1997年 / 7卷 / 07期

关键词：

D O I：

10.1016/S0960-9822(06)00208-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

That the signal transduction pathways used by the cytokines IL-2 and IL-15 are identical would suggest that these cytokines have redundant roles in lymphoid development; instead, IL-2 is the guardian of thymus-derived T-cell homeostasis, while interleukin-15 promotes extrathymic development of T and NK cells.

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页码：R424 / R426

页数：3

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