N-alkylation and [2,3]-sigmatropic rearrangement of N-allyl alpha-amino esters

被引：20

作者：

Coldham, I ^{[1
]}

Middleton, ML ^{[1
]}

Taylor, PL ^{[1
]}

机构：

[1] ICI PAINTS,SLOUGH SL2 5DS,BERKS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1997年 / 20期

关键词：

D O I：

10.1039/a705550a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Alkylation of N-allyl alpha-amino esters and [2,3]-Stevens rearrangement occur in one pot on warming in the solvent DMF, with the bases K2CO3 and DBU; this in situ formation of the quaternary ammonium salts and rearrangement of the subsequent ylides gives N,N-dialkylated allyl glycine derivatives.

引用

页码：2951 / 2952

页数：2

共 27 条

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