Bioactivity of ferrimagnetic glass-ceramics in the system FeO-Fe2O3-CaO-SiO2

被引：132

作者：

Ebisawa, Y ^{[1
]}

Miyaji, F ^{[1
]}

Kokubo, T ^{[1
]}

Ohura, K ^{[1
]}

Nakamura, T ^{[1
]}

机构：

[1] KYOTO UNIV,FAC MED,SAKYO KU,KYOTO 606,JAPAN

来源：

BIOMATERIALS | 1997年 / 18卷 / 19期

关键词：

bioactivity; ferrimagnetic glass-ceramic; apatite formation; simulated body fluid; hyperthermia treatment;

D O I：

10.1016/S0142-9612(97)00067-7

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Bioactive and ferrimagnetic glass-ceramics are useful as thermoseeds for hyperthermia treatment of cancer. A heat treatment of a 40(FeO, Fe2O3)-60CaO . SiO2 wt% glass gives a ferrimagnetic glass-ceramic containing 36 wt% magnetite in a CaO . SiO2 matrix. However, it does not show bioactivity since a small amount of iron ion remains in the matrix. In the present study, bioactivities of ferrimagnetic glass-ceramics which were prepared by heat treatment of glasses of the composition 40(FeO, Fe2O3)-60CaO . SiO2 (wt%) with various components added at 100:3 weight ratio were evaluated in vitro by examining bone-like apatite formation on their surfaces in a simulated body fluid. It was found that glass-ceramics with Na2O or B2O3 added in combination with P2O5 show bioactivity. (C) 1997 Elsevier Science Limited. All rights reserved.

引用

页码：1277 / 1284

页数：8

共 16 条

[1] SUPERPARAMAGNETISM AND FERRIMAGNETISM OF THE SMALL PARTICLES OF MAGNETITE IN A SILICATE MATRIX [J].

AURIC, P ;

VANDANG, N ;

BANDYOPADHYAY, AK ;

ZARZYCKI, J .

JOURNAL OF NON-CRYSTALLINE SOLIDS, 1982, 50 (01) :97-106

[2] BIOACTIVITY OF CAO.SIO2-BASED GLASSES - INVITRO EVALUATION [J].

EBISAWA, Y ;

KOKUBO, T ;

OHURA, K ;

YAMAMURO, T .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 1990, 1 (04) :239-244

[3]

EBISAWA Y, 1992, J MATER SCI-MATER M, V4, P225

[4]

EBISAWA Y, 1991, SERAMIKKUSU RONBUNSH, V1, P7

[5]

IKENAGA M, 1993, J ORTHOPAED RES, V6, P849

[6] SOLUTIONS ABLE TO REPRODUCE INVIVO SURFACE-STRUCTURE CHANGES IN BIOACTIVE GLASS-CERAMIC A-W3 [J].

KOKUBO, T ;

KUSHITANI, H ;

SAKKA, S ;

KITSUGI, T ;

YAMAMURO, T .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1990, 24 (06) :721-734

[7] CA, P-RICH LAYER FORMED ON HIGH-STRENGTH BIOACTIVE GLASS-CERAMIC A-W [J].

KOKUBO, T ;

ITO, S ;

HUANG, ZT ;

HAYASHI, T ;

SAKKA, S ;

KITSUGI, T ;

YAMAMURO, T .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1990, 24 (03) :331-343

[8]

KOKUBO T, 1992, BIOCERAMICS, V3, P213

[9]

KOKUBO T, 1987, YOGYO-KYOKAI-SHI, V95, P785

[10] GLASS-CERAMIC-MEDIATED, MAGNETIC-FIELD-INDUCED LOCALIZED HYPERTHERMIA - RESPONSE OF A MURINE MAMMARY-CARCINOMA [J].

LUDERER, AA ;

BORRELLI, NF ;

PANZARINO, JN ;

MANSFIELD, GR ;

HESS, DM ;

BROWN, JL ;

BARNETT, EH ;

HAHN, EW .

RADIATION RESEARCH, 1983, 94 (01) :190-198

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